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This lack of benefit might be attributed to its elevated molecular weight and reduced water solubility, both of which restricted its ability to be absorbed effectively in the striatum and impeded its passage through the bloodbrain barrier [7]

82360053), Basic Research Program of Guizhou Province (Natural Sciences) (No

Network pharmacology: a crucial approach in traditional Chinese medicine research

Previous animal studies have revealed that noise exposure can induce immediate and permanent cochlear synaptopathy 18 , as evidenced by the fact that synaptic counts measured at 0 h post-exposure are similar to those seen at 24 h, 1 wk and 8 wks thereafter 16