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Okabe K, et al

demonstrated that ES/Cu induces FDX1-independent astrocyte toxicity mediated by oxidative stress, as FDX1 knockdown did not block ES/Cu toxicity to astrocytes

For the emulsion-evaporation method, PLGA polymer was dissolved in a dispersion of DDA- GSH-AuNCs in dichloromethane, which was then emulsified into aqueous external phase