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Bloomer, Richard J., Lesley C

El compuesto se clasifica como agonista del receptor de amilina con actividad demostrada en complejos del receptor de calcitonina (CTR) y protena modificadora de la actividad del receptor (RAMP), particularmente en heterodmeros CTR/RAMP1, CTR/RAMP2 y CTR/RAMP3

reported polyamidoamine (PAMAM)-based DOX prodrug for effective tumor target 150

Using an isolated guinea pig heart model, several studies have shown that acetaminophen (0.35 mM) can increase coronary vascular resistance and positive inotropy (Merrill et al., 2001), attenuate ischemia-reduced monophasic action potentials (Merrill and Goldberg, 2001), and improve left ventricular contractility (rate of developed pressure) during post ischemiareperfusion (Merrill et al., 2001