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2025 Mar;21(3):371-382

M.SnyderA

Alcohol is metabolized to acetaldehyde in liver cells by alcohol dehydrogenase and cytochrome P450 2E1 (CYP2E1) (Seitz et al., 2018)

To explore the relevance of GSH to the distinct redox properties of FoB and MZB in vivo, we generated B cell-specific Gclc -deficient mice by crossing Gclc fl/fl mice with Mb1-Cre + mice ( Gclc fl/fl Mb1-Cre + ), in which the Cre recombinase gene is expressed under the control of the B cell-specific promoter Mb1 46