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SKU: 49069525734 · From usmivani.cz

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Description

In addition to its effect on malignant tumours, DNMT inhibitor SGI-1072 can also reduce renal aging changes by reversing the methylation of anti-aging factor KLOTHO and enhancing its expression (198), and this mechanism is related to the inhibition of oxidative stress, fibrosis and apoptosis (261)

Therefore, these concerns must be addressed before their use in clinical practice

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