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Interactions between SRCR3 and -hairpin 3 of the J chain includes a hydrogen bond (D271/O AIM -N106 J ) and a salt bridge (D271 AIM -K107 J ), as shown in Fig

Biochemistry 41:22542263 Bae S, Oh K, Kim H, Kim Y, Kim HR, Hwang YI, Lee DS, Kang JS, Lee WJ (2013) The effect of alloferon on the enhancement of NK cell cytotoxicity against cancer via the up-regulation of perforin/granzyme B secretion

Stacked Protocol (AOD + MOTS-c) Dose: 0.5 mg AOD + 10 mg MOTS-c (= 20 clicks) Duration: 4 weeks Frequency: Daily Cycle Interval: Optional 2-week pause Goal / Description: 2 weeks off, then repeat or switch to MOTS-c only maintenance Possible Side Effects AOD-9604 is generally well-tolerated in research settings