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Our patients' histories of homelessness, food insecurity, and poor nutrition made them particularly vulnerable to having restrictive diets and to a heightened risk for scurvy

This potent yet previously unrecognized pathway is regulated by cellular levels of sulfur metabolites and represents a potent cytoprotective response that might be induced in most mammalian cells under conditions that chronically elevate cytosolic cystine levels

with particularly high expression in perivascular astrocytic endfeet

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