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Although first defined in 2012, as early as 2003, when high-throughput screening revealed compounds with the ability to kill engineered tumorigenic cells, this nonapoptotic cell death, now known as ferroptosis, was initially characterized and shown to be induced by Erastin[1, 8, 9] (Figure 1)

Ahmadian, M., Roshan, V., Ashourpore, E

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Exosomes mediate sensory hair cell protection in the inner ear