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[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Shidfar F., Baghai N., Keshavarz A., Ameri A., Shidfar S

Biotin (B7) is essential for metabolism and growth, whereas folate (B9) is crucial for hematopoiesis, red blood cell formation, carbon transfer, and amino acid metabolism

However, the regulatory framework for drug development relies heavily on animal toxicology precisely because it does provide meaningful safety signals