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SKU: 5117877695
Price: 21.95 USD
Availability: InStock
Rating: 4.6165 (12 reviews)

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SKU: 5117877695 · From usmivani.cz

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Description

Pt() drugs are known to form adducts with nucleobases resulting in DNA cross-links 30 , which inhibits DNA synthesis and repair, which eventually leads to apoptosis, or programmed cell death

The UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B7, and UGT2B15 belong among the main liver xenobioticconjugating enzymes, whereas UGT1A7, UGT1A8, and UGT1A10 are predominantly extrahepatic UGT forms

Once the His-tagged protein is bound to the metal-resin, contaminating proteins can be washed away leaving the desired protein that may be eluted in a high imidazole concentration buffer