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doi:10.3390/ijms20194707 [68] Rezk M, Dawood R, Abo-Elnasr M, Al Halaby A, Marawan H

Potential role of antioxidant and anti-inflammatory therapies to prevent severe SARS-Cov-2 complications

In addition, ROS stabilize and enhance hypoxia-inducible factor-1 (HIF-1), the oxygen-sensitive subunit of the HIF-1 transcription factor, by inhibiting prolyl hydroxylasemediated degradation under both hypoxic and inflammatory conditions

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