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Some studies have reported increased markers of lipid and DNA oxidation, particularly in poorly controlled diabetic dogs, suggesting an association with disease severity [111,113]

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These studies have revealed that adolescent THC exposure induces core schizophrenia-related endophenotypes resembling positive and negative symptoms, such asocial motivation deficits, affective dysregulation, cognitive and sensorimotor gating abnormalities [4, 5]

Plasma lipid profiles improved significantly, with total cholesterol levels decreasing by approximately 30% in treated animals