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More specifically, the nuclear translocation of the YAP1 protein promoted the transcription of ACSL4 and TfR1 by binding directly to their promoters with TEAD4 and reduced the GPX4 protein level post-translationally by increasing its ubiquitination

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Ghrelin and Synthetic GH Secretagogues Protect Rat Hearts From Ischemic Damage. Basic research in cardiology.Study breakdown PubMed 10RPEP-08773Lu, Zengbing et al