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A randomized control trial by Khodabakhshi et al

Conversely, dysregulated Kla renders extensive impacts on the pathogenesis of various diseases, including cancer, neuropsychiatric disorders, cardiovascular and ophthalmic diseases, and immunoinflammatory and metabolic dysregulation, through modulating immune homeostasis, metabolic adaptation, and epigenetic remodeling

The effective and close bidirectional interactions of the oocyte with its neighboring cells, granulosa, during folliculogenesis are required for the later development of the embryo and pregnancy outcome

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