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The immune-modulating capabilities of EXOs such as regulating immune cell behavior and modulating reactions to inflammation, are critical for encouraging tissue regeneration while minimizing unfavorable immunological reactions ( Additionally, EXOs have the potential to influence immune cell polarization, promoting an anti-inflammatory phenotype

Nov 2020;69:449 e1-449 e6

With particular reference to the embodiment of providing cognitive enhancement for example, while in some cases the improvement in cognition (or the prevention of loss of cognition) that occurs may be complete, e.g

Other patients may not be able to absorb oral vitamin B12 due to surgical removal or dysfunction of the intestines in the area where absorption of vitamin B12 occurs