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Reports of severe adverse events include allergic reactions ranging from mild rashes to anaphylactic shock, kidney dysfunction particularly with high doses or prolonged use, liver toxicity in susceptible individuals, and thyroid dysfunction affecting hormone regulation

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Effects of pravastatin, a new HMG-CoA reductase inhibitor, on vitamin D synthesis in man

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in hypertensive participants, corresponding reductions were -4.85 mm Hg and -1.67 mm Hg

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