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Jul 1 2021;139(7):717-723

Additionally, we demonstrated that HIF-1 acts upstream of receptor-mediated mitophagy, based on our findings that loss of HIF-1 functionachieved through either pharmacological inhibition (PX-478) or genetic downregulationmarkedly suppressed BNIP3/NIX-mediated mitophagy

R.ThioL

1.3.1 Polymeric nanosystems Polymeric NPs may be functionalized and retained for months, and the physicochemical characteristics of these carriers could regulate drug release [89]