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These research areas may be relevant to biological pathway discussions, but they do not establish that TB-500 improves plantar fascia symptoms, mobility, running tolerance, flexibility, or sports recovery in humans

The peptide works by binding copper ions and acting as a signaling molecule

Results The AngIV Analog D-Nle-Tyr-Ile-NH(CH 2 ) 5 CONH 2 is More Metabolically Stable than Norleual (Nle-Tyr-Leu--(CH 2 NH 2 ) 3-4 -His-Pro-Phe (SEQ ID NO: 1): The AngIV-related peptidomimetic Norleual was previously shown to possess, anti-HGF/Met, anti-angiogenic, and anti-cancer activities (Yamamoto et al., 2010)