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Consistently, animal studies and clinical imaging have provided evidence that disrupted MET signaling produces functional as well as morphological alterations in neurons in those brain regions implicated in ASD endophenotypes (reviewed in Peng et al., 2013

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J Neurochem 72:17501758 Kussmaul L, Hamprecht B, Dringen R (1999) The detoxification of cumene hydroperoxide by the glutathione system of cultured astroglial cells hinges on hexose availability for the regeneration of NADPH