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The gene of CTGF, a matricellular protein, is a straightforward downstream initial response gene of the TGF- 1 (Lee et al., 2015)

Next-generation nanocarrier development will likely focus on biomimetic and cell-derived nanoparticlessuch as those cloaked in cell membranes or derived from exosomesoffering enhanced biocompatibility, reduced immunogenicity, and improved targeting through natural ligand-receptor interaction

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In this scenario, plant-based phytochemicals are becoming an alternative choice for drug designing