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Dental Amalgam: Additional Resources Dental Amalgam Regulation Documents Dental Devices: Classification of Dental Amalgam, Reclassification of Dental Mercury, Designation of Special Controls for Dental Amalgam, Mercury, and Amalgam Alloy (Final Rule) Dental Amalgam, Mercury, and Amalgam Alloy - Class II Special Controls Guidance for Industry and FDA Staff Appendix I: Summary of Changes to the Classification of Dental Amalgam and Mercury White Paper: FDA Update/Review of Potential Adverse Health Risks Associated with Exposure to Mercury in Dental Amalgam FDA Literature Reviews Epidemiological Evidence on the Adverse Health Effects Reported in Relation to Mercury from Dental Amalgam: Systematic Literature Review (2010-Present) (Published September 2019) Addendum to the Dental Amalgam White Paper: Response to 2006 Joint Advisory Panel Comments and Recommendations (Published July 2009) White Paper: FDA Update/Review of Potential Adverse Health Risks Associated with Exposure to Mercury in Dental Amalgam (Published July 2006) FDA Safety Communications Recommendations About the Use of Dental Amalgam in Certain High-Risk Populations: FDA Safety Communication FDA's Informational Brochure - Information for Patients About Dental Amalgam Fillings Advisory Committee Meetings Immunology Devices Panel of the Medical Devices Advisory Committee Meeting (November 2019) Dental Products Panel Medical Devices Advisory Committee Meeting (December 2010) Other Resources The following links to the Agency for Toxic Substances and Disease Registry (ATSDR) website and the Environmental Protection Agency (EPA) website provide additional information about sources of mercury exposure, environmental aspects, and bioaccumulation