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Pugliese N, di Tommaso L, Lleo A, et al

Others It has been demonstrated that exposure to benzo(a)pyrene (BaP) or its metabolite BPDE (benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide) results in the expression of the E3 ligase MARCHF1, which in turn ubiquitinates and degrades GPX4