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At the same time, it was speculated that the stem cells may down-regulate the expression of IL-6, IL-8, and TNF- through paracrine mechanisms, thus delaying the progression of IDD [35]

However, despite these substances are able to interfere with iodine uptake in the thyroid, the consumption of reasonable amounts of foods containing goitrogens is not a concern for people who have adequate iodine intakes and eat a variety of foods, and there are no contraindications to their consumption, as detailed below [53]

The assessment of results was made at 24 and 96 hours after peptide administration and included changes in the kidneys on a scale from 0 to 3, where: 0 - healthy kidney, 1 - mild hydronephrosis, 2 - moderate hydronephrosis, visible dilation of the renal pelvis, few changes on the kidney surface, 3 - severe hydronephrosis, dilation of the renal pelvis, thinning of the renal parenchyma, and a significant number of changes on the kidney surface