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doi:10.1038/nchembio711 Fuchs Y, Steller H (2011) Programmed cell death in animal development and disease

Fun fact: In Pakistan, locally grown apples from Balochistan are among the richest in antioxidants especially the red and green varieties

191 In diabetic wounds, excessive NET formation triggers activation of the NOD-like receptor protein 3 (NLRP3) inflammasome and induces the release of IL-1 in macrophages via the TLR-4/TLR-9/ nuclear factor enhancer of activated B cells (NF-B) signaling pathway

Understanding fundamental molecular and genetic mechanisms is necessary to develop new therapeutic approaches for NSCLC