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Compared with the NC group, crystal formation in the urolithiasis model group was signifi-cantly increased, and renal tubules were dilated and vacuolated, leading to glomerular degeneration

We developed a multi-dimensional attribute ranking approach integrating multi-omics data with liver histology and prior knowledge uncovering known human markers, but also novel candidates

These compounds are known to play a role in glutathione production, which helps combat oxidative stress and supports metabolic processes [1][2]

Therefore, the structure of the erastin-bound SLC7A11 will inspire further research to design better versions of erastin as ferroptosis inducers and anti-cancer drugs