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Animals were treated every other day for two weeks, and monitored for drug related toxicity (body weight) and diabetes onset (BG 350 mg/dl)

One significant positive in this study is that they also used laser Doppler scanning (recovery of blood flow in the ischemic muscle) to indicate the promotion of angiogenesis alongside Western blot and real-time PCR for the expression of VEGFR2

The evidence base consists primarily of preclinical studies in animal models, with limited clinical data in humans

Recently, we demonstrated that H 2 S 2 and H 2 S 3 as well as H 2 S are produced by 3-mercaptopyruvate sulfur transferase (3MST) 14