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The value is adjunctive: they prevent hepatic fat accumulation during aggressive calorie restriction, and they correct B12 deficiency that would otherwise limit exercise capacity and metabolic rate

Approach Short trial arm Duration 12 weeks Review Point Week 12 Notes METAOD005 used 12 weeks at oral doses 1-30 mg/day in 300 obese adults

What This Means in Practice The research on AHK-Cu and dermal papilla cells is more specific and mechanistically detailed than what exists for most topical hair ingredients

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