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Often, a few weeks of therapy will markedly improve symptoms related to chronic disease and allow for the transition to appropriate oral supplements.IV therapy with nutrients may be needed only a few times or twice weekly for an extended period

Worsening of bulbar symptoms leading to myasthenic crisis can occasionally be precipitated by high dose steroids, although is less likely to occur with gradual titration of the dose with close monitoring

MeHg also increases the spontaneous release of glutamate from mouse cerebellar slices (Reynolds and Racz, 1987) and cultured neuronal cells (Vendrell et al., 2007), suggesting that increased glutamate release also contributes to elevated extracellular glutamate levels after MeHg exposure