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Fatigue or Dizziness: Transient lethargy has been noted early on, possibly from metabolic shifts or inflammation reduction

10.1016/j.nbd.2011.12.025 70 LoewenJ

[78] Mechanisms of smoking mediating the development of PCT remain unclear, but increased oxidative stress and induction of hepatic cytochrome P450 enzymes are thought to contribute to disease pathology