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Lancet ;398(10317): 2160-2172 View at Publisher | View at Google Scholar Frias JP, Deenadayalan S, Erichsen L, Knop FK, Lingvay I, et al

(2015) reported that both TRPV1 knockout and pharmacological inhibition of the channel in an ex vivo model of increased IOP, resulted in fewer RGCs labeled for an apoptotic marker, suggesting that the entry pathway of TRPV1 Ca 2+ could be related to cell death (Sappington et al., 2015)