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Abbreviations AD: Alzheimers disease PD: Parkinsons disease ALS: Amyotrophic lateral sclerosis HD: Huntingtons disease ATP: Adenosine triphosphate ROS: Reactive oxygen species TCA: Tricarboxylic acid ETC: Electron transport chain mtDNA: Mitochondrial DNA PET: Positron emission tomography APOE4: Apolipoprotein E4 PRKN: Parkin PINK1: Phosphate and tensin homolog-induced kinase 1 PGC-1: Peroxisome proliferator-activated receptor- coactivator-1 C9orf72: Chromosome 9 open reading frame 72 SOD1: Superoxide dismutase 1 FUS: Fused in sarcoma TDP-43: Transactive response DNA binding protein 43 HTT: Huntingtin References Ovid