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28 KwonK.ChoiD.HyunJ.JungH.BaekK.ParkC

With the global aging population, AD prevalence has been steadily increasingapproximately 3%7% of individuals over 65 years are affected, with risk nearly doubling every 5 years

Conversely, if a patient presents with pernicious anemia or severe neurological signssuch as intense tingling in the hands, memory loss, or muscle weaknessthe dosage remains the same (usually 1,000 mcg), but the frequency increases significantly

Additionally, it is thought that peripheral innate immune cells have reduced function following stroke, including impaired neutrophil oxidative burst and NETosis [18]