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The angiogenic effect of copper has been well-recognized, which is presumed to attribute to the regulation of factors involved in vessel formation and maturation, especially the pro-angiogenic factor, namely vascular endothelial growth factor (VEGF), and its major transcription factor, namely hypoxia-inducible factor-1-alpha (HIF1) [36]

Future research should prioritize larger, long-term RCTs with standardized protocols to strengthen the evidence base

Since the effect of cold laser therapy on unborn children is unknown, its suggested that pregnant women avoid this type of treatment

Detection of soluble intercellular adhesion molecule1 and vascular cell adhesion molecule1 in both cerebrospinal fluid and serum of patients after aneurysmal subarachnoid hemorrhage