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NHPN-1010 promoted functional normalization from noise-induced hearing loss as reflected in electrophysiological measures With pre-exposure measurements serving as the baseline, auditory sensitivity was evaluated by ABR recordings following noise exposure and subsequent treatment in the chronic phase

Furthermore, targeting the CoQ10-FSP1 axis sensitizes Keap1 mutant lung cancer cells or tumors to radiation by inducing ferroptosis (Koppula et al., 2022)

FIGURE 6 Cellular Validation of the Specificity of GPX4 Activator To further evaluate the selectivity and specificity of compound 102 in a cellular context, we employed the cellular thermal shift assay (CETSA