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The data acquired using multiple omics platforms may be evaluated individually in each omics dataset to discover biomarkers, or multiple omics datasets can be integrated to obtain a more comprehensive systems biology biomarker of the drug-induced hepatotoxicity (Ilyin et al

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[] LCAT maintains the homeostasis of bone (a balance between bone resorption mediated by osteoclasts and bone formation mediated by osteoblasts) through modulating intracellular cholesterol levels (intracellular cholesterol levels are positively related to osteoclast differentiation but negatively related to osteoblast differentiation)