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Disruption of this microbiome-host symbiosis contributes to the initiation and progression of immune and metabolic diseases, such as IBD 73 , graft-versus-host diseases (GvHD) 74 , and type 2 diabetes 75 , underlining the proposition that microbe-host interactions are critically important for human health 76

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Genotoxicity: damage to DNA and its consequences

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Furthermore, patients with inflammatory bowel disease have a higher risk of HHcy due to vitamin B deficiency

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High serum riboflavin is associated with the risk of sporadic colorectal cancer

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