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The treatment of tumors formed by the radio-resistant GSCs with an IGF1R inhibitor results in a marked increase in radio sensitivity, suggesting that the blockade of IGF1R signaling is an effective strategy to reverse radio-resistance (Osuka et al., 2013)

Injection frequency: AOD 9604 requires daily injection

Es gestaltet sich als herausfordernd und kostenintensiv, die Konzentration von Glutathion im Blut mittels oral verabreichter Prparate zu erhhen, da das Enzym Gamma-Glutamyltranspeptidase im Darm vorhanden ist und Glutathion dort abbaut