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Antioxidant and inflammatory cytokine in tears of patients with dry eye syndrome treated with preservative-free versus preserved eye drops

Cell Stem Cell 26 , 97107.e106 (2020)

Their enhanced bioactivity relative to bulk copper is primarily attributed to the higher density of grain boundaries at the nanoscale, which facilitates accelerated copper ion release and promotes the generation of ROS (Sundberg et al., 2015)