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Cui and Qu, 2021), meaning most pyruvate is channelled toward L-lactic acid formation rather than alternative products such as ethanol or acetic acid

This might have resulted in a heterogeneous study population but reflects the clinical situation

For example, nitrofurantoin (Macrobid), characteristically causes a chronic hepatitis after many weeks, months or even years of therapy with some cases presenting with cirrhosis associated with serum antinuclear antibodies (ANA) [35]