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For instance, in atherosclerosis models, macrophage-targeted nanoparticles have been utilized to deliver drugs directly to macrophages within the plaques (237)

doi: 10.1016/j.isci.2023.107487 51 WangDWangXTanBWenXYeSWuYet al

(Figure 3A,B) Consider in vivo GSH concentration of 110 mM, second-order reaction rate k GSH around 0.048 0.48 M 1 min 1 translates to a half-life of 24 h