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In this experiment, we used a human tracheal epithelial cell line, BEAS-2B, that was retrovirally transformed with activated oncogenes: BRAF V600A , EGFR L858R , or PI3K H1017R [41]

*Correspondence: Quansheng Feng, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Cyclic voltammetry Ferrocene (0.5 mM) was mixed with GSH and GSSSG in N 2 -saturated BrittonRobinson buffer (0.04 M boric acid, 0.04 M phosphoric acid and 0.04 M acetic acid) at pH 9