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Australian and New Zealand journal of medicine

Many patients do extremely well on the lower end when paired with a topical 2 %3 % serum and good sun protection

doi: 10.1074/jbc.M205225200

Moreover, hormonal changes with aging such as insulin resistance, lower IGF-1 levels, and higher glucocorticoid levels can tilt the balance toward a catabolic state, meaning geriatric patients often have a blunted anabolic response even with adequate nutrients [69, 70]