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Molecular cell 86(2):407-422.e6, 2026

Gao, J., Reggiori, F

The interesting point about the binding of drugs to aptamers is that by changing the length of the aptamer and its physicochemical features, the number of conjugating molecules can be increased without any particular effect on the affinity and specificity of the aptamer [211, 216]

Furthermore, the same polymorphism was found to be over-represented in patients developing acute liver injury following high doses of paracetamol taken unintentionally over several days [39]