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Acetaminophen) is one of the most used over-the-counter antipyretics and analgesics among pediatrics with well-established safety and efficacy compared to other analgesics and antipyretics [1,2,3]

In summary, immune dysregulation in bipolar disorder is associated with alterations in monoamine and glutamate signaling, impaired neuroplasticity and neurotrophic support, and changes in glial and neuronal function, most likely contributing to the symptomatic expression and medical comorbidities of this mood disorder

BMC Medicine

Neuroimaging findings revealed caudate atrophy (CA) and putamen atrophy (PA) in all patients, with 55.56% exhibiting concomitant putaminal rim signs [Table 1