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do not find leukocytes infiltration in the liver parenchyma during APAP-induced ALF, probably because IL-5 causes liver injury in a leukocyte-independent manner or that IL-5 expression is an indirect consequence of liver injury and has no effect on pathology [209]

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For instance, appropriately timed light therapy has been shown to re-entrain disrupted circadian rhythms and mitigate renal dysfunction in diabetic nephropathy (Thomas and Cooper, 2010)

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