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Second, a specific concentration of the cationicity of aNDBs must be achieved to reach a multivalence effect (Smola-Dmochowska et al., 2023) that results in the simultaneous binding of aNDB molecules to the bacterial cell structures and moving to the next step

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Results Preclinical Assessment of Immunogenic Risk for AMG 966 In order to assess the immunogenic risk of AMG 966 and the charge pair mutations ( Supplementary Figure 1 ), an in silico analysis of MHC class II binding was performed using the Immune Epitope Database (IEDB) tool