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melanoma) exhibits a higher proportion of monocyte-derived macrophages (MDMs), lymphocytes and neutrophils [9]

Biomed Pharmacother= Biomed Pharmacother 143, 112139

In the present investigation, the reduced activity of ALT and AST enzymes and creatinine levels in T1_HS and T2_HS groups may be attributed to the enhanced antioxidant enzyme activity (GPx, SOD, catalase) and lower MDA levels in these groups 7,11

a neurotransmitter deficiency state including the elevation of GABA (gamma-amino-benzoic acid), PEA (phenyl-ethyl-amine), and histamine, and more generally any abnormal alteration of excitatory or inhibitory neurotransmitters that result in a disease state