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Pulmonary Fibroblast Models Pathological fibrosis, an endpoint of many chronic inflammatory diseases, involves the excessive deposition of ECM by activated fibroblasts

Lee SB, Kim JJ, Han SA, Fan Y, Guo LS, Aziz K, et al

In a subsequent exploratory analysis of the pivotal Phase III trial, among patients receiving CPX-351 consolidation, CPX-351 was administered entirely as outpatient in 51% of the cases during the first consolidation cycle, and in 61% during the second cycle

C 2 in the imidazole ring is positioned between two nitrogen atoms, and it has a unique ability to exchange its proton with a deuteron in an irreversible spontaneous reaction