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Primary glial cells cultured in vitro, after being infected with COVID-19, proved to secrete a considerable amount of inflammatory mediators such as IL-6, IL-12, IL-15, and TNF- [12]

However, human epidemiological studies have yielded inconsistent findings, reporting higher 239,240 , lower 241,242,243,244,245 , or unchanged 246 blood Mn levels in patients with T2DM than in controls