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The enzymes of glutathione metabolism: an overview

Severe AMS, however, is associated with the development of other high-altitude illnesses, such as high-altitude cerebral edema (HACE) and/or high-altitude pulmonary edema (HAPE), both potentially life-threatening and characterized by vasogenic edema, altered vascular permeability, and neurological or respiratory dysfunction (Moraga et al., 2007

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They suggested that acquired cysteines often play a role in tumourigenesis [113], probably by contributing to tumour suppressor genes inactivation and oncogenes activation